Results: Psoriasis is linked with many mental disorders, both in the psychotic and neurotic sprectrum. Chronic stress diminishes hypothalamic-pituitary-adrenal axis and upregulates sympathetic-adrenal-medullary responses, stimulating pro-inflammatory cytokines.
Increased severity of psoriasis can lead to increased depression and vice versa. Females, children, and elderly with psoriasis are more vulnerable to depression than men. Social stigmatization and low self-esteem secondary to psoriasis play a significant role in causing depression in patients with psoriasis.
Psoriasis is a condition independent of stress or anxiety. However, stress or anxiety can trigger or worsen psoriasis symptoms. One study has suggested that anxiety and psoriasis have a cyclical relationship. This means that psoriasis can cause anxiety and that anxiety can cause the symptoms of psoriasis to worsen.
Can psoriasis cause schizophrenia?
This study is the first systematic review and meta-analysis to comprehensively combine all available data on the risk of schizophrenia among patients with psoriasis. A significantly elevated risk was found with 41% increased odds of schizophrenia compared with subjects without psoriasis.
Does psoriasis affect brain?
Psoriasis affects your brain chemicals.
These make skin cells grow out of control and form scaly plaques. They also change levels of chemicals in your brain that affect your mood. A cytokine called TNF-alpha may affect brain chemicals like serotonin in a way that could lead to depression.
Does psoriasis affect life expectancy?
Patients with mild psoriasis are not associated with higher rates of mortality as compared to the general population, and the life expectancy is considered to be equal. However, mortality rates may be affected in severe cases of psoriasis.
Can psoriasis cause anger?
Objective: Psoriasis is one of the most common chronic skin diseases, which has a negative impact on the interpersonal relationship and psychosocial well-being. Therefore, psoriasis may lead to a decrease in the self-esteem of the patients. Increased level of anger often accompanies patients with psoriasis.
Can psoriasis make you suicidal?
Data from a systematic review and meta-analysis showed patients with psoriasis were twice as likely to consider suicide than the general population. Additionally, psoriasis was significantly associated with both attempted and completed suicide, researchers reported.
What organs can be affected by psoriasis?
Psoriasis is an autoimmune condition that causes widespread inflammation. This can affect the skin and several other parts of the body, including the lungs.
What is the root cause of psoriasis?
Psoriasis occurs when skin cells are replaced more quickly than usual. It’s not known exactly why this happens, but research suggests it’s caused by a problem with the immune system. Your body produces new skin cells in the deepest layer of skin.